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M3189

Sigma-Aldrich

Mepivacaine hydrochloride

98.0-102.0%, meets USP testing specifications

Sinónimos:

1-Methyl-2′,6′-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C15H22N2O · HCl
Número de CAS:
1722-62-9
Peso molecular:
282.81
Número CE:
217-023-9
Número MDL:
MFCD00144738
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
57654370
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Agency

meets USP testing specifications

Ensayo

98.0-102.0%

emisor

Novocol

cadena SMILES

CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl

InChI

1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H

Clave InChI

RETIMRUQNCDCQB-UHFFFAOYSA-N

Información sobre el gen

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Acciones bioquímicas o fisiológicas

Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current.
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

Características y beneficios

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Novocol. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Aplicación

Referencia del producto
Descripción
Precios

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301,H336

Clasificaciones de peligro

Acute Tox. 3 Oral - STOT SE 3

Órganos de actuación

Central nervous system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
SLBK4373V
SLBG7495V
SLBC9892V
081M1441V
120M1861V

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Visite la Librería de documentos

Mylène Lecours et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 60(3), 244-252 (2012-12-06)
In recent studies on ultrasound-guided infraclavicular block (ICB), the authors have favoured a single injection posterior to the axillary artery rather than multiple injections; however, procedural complications and success rates associated with single-injection ultrasound-guided ICB are not well known. We
Kaoru Hara et al.
Regional anesthesia and pain medicine, 37(3), 289-293 (2012-04-06)
The present study was conducted to determine the incidence of unintentional intraneural injection during ultrasound-guided subgluteal sciatic nerve block using a low-frequency transducer. We also observed the effects of intraneural injection using ropivacaine and mepivacaine. Enrolled in the study were
T Kjelstrup et al.
Acta anaesthesiologica Scandinavica, 56(7), 914-919 (2012-05-11)
Axillary block is the most commonly performed brachial plexus block and may be guided by nerve stimulation or ultrasound. Magnetic resonance imaging (MRI) has proven to be beneficial in presenting anatomy of interest for regional anaesthesia and in demonstrating spread
Mi Hyeon Lee et al.
Pain medicine (Malden, Mass.), 13(11), 1381-1388 (2012-09-28)
Compared with the blind technique, ultrasound-guided stellate ganglion block (SGB) reduces the amount of local anesthetic needed for a successful block. The purpose of this study is to determine the minimal, optimal volume of local anesthetic required for successful ultrasound-guided
Hui-Jin Sung et al.
Canadian journal of physiology and pharmacology, 90(7), 863-872 (2012-06-19)
Mepivacaine is an aminoamide-linked local anesthetic with an intermediate duration that intrinsically produces vasoconstriction both in vivo and in vitro. The aims of this in-vitro study were to examine the direct effect of mepivacaine in isolated rat aortic rings and
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Chromatograms

application for HPLC

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