H9250
Histone from calf thymus
Type II-A, lyophilized powder
Sinónimos:
histone type VIII-S
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| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
100 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 133,00 € |
500 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 525,00 € |
Acerca de este artículo
Número CAS:
UNSPSC Code:
41106305
NACRES:
NA.51
Beilstein/REAXYS Number:
1895465
MDL number:
Form:
lyophilized powder
Biological source:
bovine (calf) thymus
133,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarlebiological source
bovine (calf) thymus
Quality Segment
type
Type II-A
form
lyophilized powder
application(s)
cell analysis
storage temp.
2-8°C
General description
Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.
Application
Histone from calf thymus has been used:
- in methyltransferase reaction mixture for methyltransferase assay[1]
- in in vitro binding assay, to explore the potential binding of the MORF4 (mortality factor on chromosome 4) - related gene on chromosome 15 (MRG15) chromo domain with histone
- in in vitro coculture assays, to stimulate liver resident Kupffer cells
Biochem/physiol Actions
The core histones are involved in histone-histone interactions and maintains the organization of the nucleosomal DNA. The histone tail helps in forming higher-order nucleosomal structures. The overall structure and action of chromatin fiber is regulated by histone modifications.
Features and Benefits
Do not confuse Sigma "Type" designations with the "Fraction" designations used by Luck and co-workers.
Preparation Note
Unfractionated whole histone
1 of 1
Este artículo | |||
|---|---|---|---|
| biological source bovine (calf) thymus | biological source bovine (calf) thymus | biological source human | biological source human |
| form lyophilized powder | form powder | form liquid | form liquid |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| type Type II-A | type Type III-S | type - | type - |
| application(s) cell analysis | application(s) - | application(s) cell analysis | application(s) - |
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Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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