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Merck

GW22757

Sigma-Aldrich

Anti-AKT1 (ab1) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

chicken

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

reactividad de especies

rat, human, mouse

fabricante / nombre comercial

Genway 15-288-22757

técnicas

western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... AKT1(207)

Categorías relacionadas

Inmunógeno

Immunogen Sequence: GI # 62241011, sequence 2-200
Recombinant serine/threonine protein kinase

Aplicación

Anti-AKT1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Acciones bioquímicas o fisiológicas

RAC-α serine/threonine-protein kinase is an enzyme encoded by the AKT1 gene in humans and is a member of the serine/threoine AGC protein kinase family. It is an intracellular signal transduction protein activated by growth hormones and its pathway is critically involved in cancer cell growth, proliferation, metabolism, invasion and survival. AKT1 acts as a potential target for cancer gene therapy. The gene is frequently activated in a variety of cancer types and is accepted as a promising anticancer therapeutic target.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Min Zhang et al.
Clinical laboratory, 60(1), 1-8 (2014-03-08)
AKT1 is a member of the serine/threoine AGC protein kinase family involved in cancer's metabolism, growth, proliferation, and survival. It is a potential target for cancer gene therapy. In the present study, we used DNAzyme and siRNA technology to inhibit
Alpaslan Mayadagli et al.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 19(1), 157-163 (2014-03-25)
Akt, also known as protein kinase B (PKB), is an intracellular signal transduction protein activated by growth hormones. PKB/Akt is frequently activated in a variety of cancer types, but its role in the development and progression of lung cancer has
F Yang et al.
Cell death & disease, 5, e1114-e1114 (2014-03-15)
The serine/threonine kinase AKT is generally accepted as a promising anticancer therapeutic target. However, the relief of feedback inhibition and enhancement of other survival pathways often attenuate the anticancer effects of AKT inhibitors. These compensatory mechanisms are very complicated and
Xiaoting Wang et al.
Journal of cancer research and clinical oncology, 140(8), 1399-1411 (2014-04-17)
v-akt Murine thymoma viral oncogene homolog (AKT) pathway is critically involved in cancer cell growth, invasion, and survival. We examined the correlation between the genetic variations in molecules of AKT pathway and clinical outcomes of gastric cancer. Six single nucleotide

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