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EHU013081

Sigma-Aldrich

MISSION® esiRNA

targeting human HES1

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About This Item

Código UNSPSC:
41105324
NACRES:
NA.51

descripción

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Línea del producto

MISSION®

formulario

lyophilized powder

secuencia objetivo ADNc esiRNA

GGTGCTGATAACAGCGGAATCCCCCGTCTACCTCTCTCCTTGGTCCTGGAACAGCGCTACTGATCACCAAGTAGCCACAAAATATAATAAACCCTCAGCACTTGCTCAGTAGTTTTGTGAAAGTCTCAAGTAAAAGAGACACAAACAAAAAATTCTTTTTCGTGAAGAACTCCAAAAATAAAATTCTCTAGAGATAAAAAAAAAAAAAAAAGGAAAATGCCAGCTGATATAATGGAGAAAAATTCCTCGTCCCCGGTGGCTGCTACCCCAGCCAGTGTCAACACGACACCGGATAAACCAAAGACAGCATCTGAGCACAGAAAGTCATCAAAGCCTATTATGGAGAAAAGACGAAGAGCAAGAATAAATGAAAGTCTGAGCCAGCTGAAAACACTGATTTTGGATGCTCTGAAGAAAGATAGCTCGCGG

Ensembl | nº de acceso humano

ENSG00000114315

Nº de acceso NCBI

NM_005524

Condiciones de envío

ambient

temp. de almacenamiento

−20°C

Información sobre el gen

human ... HES1(3280) , HES1(3280)

Descripción general

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Información legal

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Jiadi Wen et al.
Orphanet journal of rare diseases, 8, 100-100 (2013-07-11)
Rare, recurrent genomic imbalances facilitate the association of genotype with abnormalities at the "whole body" level. However, at the cellular level, the functional consequences of recurrent genomic abnormalities and how they can be linked to the phenotype are much less
Xiaoping Du et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 26(5), 1313-1326 (2018-04-24)
Deafness is commonly caused by the irreversible loss of mammalian cochlear hair cells (HCs) due to noise trauma, toxins, or infections. We previously demonstrated that small interfering RNAs (siRNAs) directed against the Notch pathway gene, hairy and enhancer of split 1
Ethan V Abel et al.
PloS one, 9(3), e91983-e91983 (2014-03-22)
Pancreatic cancer stem cells (CSCs) represent a small subpopulation of pancreatic cancer cells that have the capacity to initiate and propagate tumor formation. However, the mechanisms by which pancreatic CSCs are maintained are not well understood or characterized. Expression of
C-R Pradeep et al.
Oncogene, 31(7), 907-917 (2011-07-12)
A large fraction of ductal carcinoma in situ (DCIS), a non-invasive precursor lesion of invasive breast cancer, overexpresses the HER2/neu oncogene. The ducts of DCIS are abnormally filled with cells that evade apoptosis, but the underlying mechanisms remain incompletely understood.
G Fiaschetti et al.
British journal of cancer, 110(3), 636-647 (2013-12-19)
microRNA-9 is a key regulator of neuronal development aberrantly expressed in brain malignancies, including medulloblastoma. The mechanisms by which microRNA-9 contributes to medulloblastoma pathogenesis remain unclear, and factors that regulate this process have not been delineated. Expression and methylation status
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