E1257

Epidermal Growth Factor from murine submaxillary gland

lyophilized powder, BioReagent, suitable for cell culture

• Sinónimos: EGF, Epidermal cell growth factor
• Número de CAS: 62229-50-9
• Número CE: 263-468-7
• Número MDL: MFCD01634807
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: mouse submaxillary glands
• Nivel de calidad: 200
• Línea del producto: BioReagent
• Análisis: ≥98% (SDS-PAGE)
• formulario: lyophilized powder
• potencia: 0.02-2.0 ng/mL EC₅₀
• envase: pkg of 0.1 mg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• técnicas: cell culture | mammalian: suitable
• impurezas: endotoxin, tested
• color: white
• Nº de acceso UniProt: P01132
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: mouse ... Egf(13645)

Descripción

Descripción general

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

Aplicación

Epidermal Growth Factor from murine submaxillary gland has been used

• in studying its effects on the development of caustic esophageal stricture in rats
• for preparation of MCF-10A cell line
• for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

Acciones bioquímicas o fisiológicas

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

Forma física

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

Nota de preparación

Purified by gel filtration and ion-exchange chromatography.

Nota de análisis

The biological activity is measured in a proliferation assay using BALB/MK cells.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)