D3758
DL-2,4-Diaminobutyric acid dihydrochloride
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Fórmula lineal:
NH2CH2CH2CH(NH2)COOH · 2HCl
Número CAS:
Peso molecular:
191.06
UNSPSC Code:
12352200
NACRES:
NA.26
PubChem Substance ID:
EC Number:
265-774-6
Beilstein/REAXYS Number:
4708499
MDL number:
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≥98% (TLC)
form
powder
color
white
mp
197 °C (dec.) (lit.)
application(s)
detection
storage temp.
−20°C
SMILES string
Cl.Cl.NCCC(N)C(O)=O
InChI
1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H
InChI key
CKAAWCHIBBNLOJ-UHFFFAOYSA-N
Biochem/physiol Actions
DL-2,4-Diaminobutyric acid is a racemic mixture of the selective GABA uptake inhibitors L-DABA and D-DABA. DL-2,4-diaminobutyric acid is found in cell-wall peptidoglycan of Leifsonia bigeumensis sp. Nov.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Sandra M Leal et al.
Journal of neurobiology, 61(2), 189-208 (2004-09-25)
We have identified specific GABAergic-modulated behaviors in the juvenile stage of the fruit fly, Drosophila melanogaster via systemic treatment of second instar larvae with the potent GABA transport inhibitor DL-2,4-diaminobutyric acid (DABA). DABA significantly inhibited motor-controlled body wall and mouth
Syed G Dastager et al.
International journal of systematic and evolutionary microbiology, 58(Pt 8), 1935-1938 (2008-08-05)
A Gram-positive, motile, mesophilic bacterium that formed yellowish-white, circular, convex, glistening colonies, strain MSL-27T, was isolated from a soil sample from Bigeum Island, Korea, and its taxonomic position was investigated by a polyphasic approach. Cells of strain MSL-27T are non-spore-forming
Amanda J Foss et al.
Toxicon : official journal of the International Society on Toxinology, 152, 150-159 (2018-08-14)
β-Methylamino-L-alanine (BMAA) has been identified as the potential cause of the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC) observed in the Chamorro people of Guam. The principal hypothesis for BMAA exposure and intoxication relies on the biomagnification of BMAA in flying fox
Shuqin Wang et al.
Toxicon : official journal of the International Society on Toxinology, 173, 39-47 (2019-11-18)
Neurotoxin β-N-methylamino-L-alanine (BMAA) has been widely detected in diverse aquatic organisms within different ecosystem trophic levels in recent years. It was the goal of this study to investigate the accumulation and tissue distribution of BMAA in marine opossum shrimp (Neomysis
Sandra M Leal et al.
Journal of neurobiology, 50(3), 245-261 (2002-01-26)
We have identified several GABAergic-modulated behaviors in Drosophila melanogaster by employing a pharmacological approach to disrupt GABA transporter function in vivo. Systemic treatment of adult female flies with the GABA transport inhibitors DL-2,4-diaminobutyric acid (DABA) or R,S-nipecotic acid (NipA), resulted
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