D1814

Anti-DcR3 antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-Decoy Receptor 3, Anti-TNFRSF6B, Anti-TR6
• Número MDL: MFCD02686088
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 33 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~0.5 mg/mL
• técnicas: microarray: suitable; western blot: 1:500-1:1,000 using human heart, brain or kidney lysates
• Nº de acceso UniProt: O95407
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TNFRSF6B(8771) ; mouse ... Dcr3(497118)

Descripción

Descripción general

It is a member of the tumor necrosis factor receptor superfamily (TR6). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Inmunógeno

synthetic peptide corresponding to amino acids 31-46 of human DcR3 precursor.

Aplicación

Anti-DcR3 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1000 using human heart, brain or kidney lysates.

Acciones bioquímicas o fisiológicas

DcR3 is a soluble decoy receptor that binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis.

Forma física

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.