C6767

Congo Red

Dye content ≥35 %, Powder

• Sinónimos: Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y
• Fórmula empírica (notación de Hill): C₃₂H₂₂N₆Na₂O₆S₂
• Número de CAS: 573-58-0
• Peso molecular: 696.66
• Número de índice de color: 22120
• Beilstein: 3894858
• Número CE: 209-358-4
• Número MDL: MFCD00004028
• Código UNSPSC: 12171500
• ID de la sustancia en PubChem: 24892892
• NACRES: NA.47

Propiedades

• product name: Congo Red, Dye content ≥35 %
• formulario: powder
• Nivel de calidad: 200
• composición: Dye content, ≥35%
• técnicas: titration: suitable
• color: red-brown
• pH: 6.7 (10 g/L)
• mp: >360 °C (lit.)
• solubilidad: H₂O: 1 mg/mL
• aplicaciones: diagnostic assay manufacturing; hematology; histology
• temp. de almacenamiento: room temp
• cadena SMILES: [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O
• InChI: 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
• Clave InChI: IQFVPQOLBLOTPF-HKXUKFGYSA-L

Descripción

Aplicación

• Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues.
• It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans.
• It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.

Acciones bioquímicas o fisiológicas

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H350,H361d
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Carc. 1B - Repr. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges