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Merck

C0791

Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse

clone KS-1A3, ascites fluid

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
KS-1A3, monoclonal
Application:
ARR, IF, IHC (p)
Citations:
9

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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

KS-1A3, monoclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect immunofluorescence: 1:100 using formalin-fixed, paraffin-embedded human tissue sections.1, microarray: suitable

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KRT13(3860)

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1 of 4

Este artículo
C1399C5176C2931
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

clone

KS-1A3, monoclonal

clone

KS-B17.2, monoclonal

clone

6B10, monoclonal

clone

C-11, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

human

species reactivity

rabbit, feline, hamster, goat, guinea pig, human, canine, sheep

species reactivity

bovine, mouse, frog, human, kangaroo rat, rat

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

Gene Information

human ... KRT13(3860)

Gene Information

human ... KRT18(3875)

Gene Information

human ... KRT4(3851)

Gene Information

bovine ... Krt1(100301161)
human ... KRT1(3848), KRT13(3858), KRT13(3858), KRT18(3875), KRT18(3875), KRT4(3851), KRT4(3851), KRT5(3852), KRT5(3852), KRT6A(3868), KRT6A(3868), KRT6B(3854), KRT6B(3854), KRT8(3856), KRT8(3856)
mouse ... Krt1(16678), Krt10(16661), Krt10(16661), Krt13(16663), Krt13(16663), Krt18(16668), Krt18(16668), Krt4(16682), Krt4(16682), Krt5(110308), Krt5(110308), Krt6a(16687), Krt6a(16687), Krt6b(16688), Krt6b(16688), Krt8(16691), Krt8(16691)
rat ... Krt1(300250), Krt1-18(706059), Krt1-18(706059), Krt10(450225), Krt10(450225), Krt2-5(369017), Krt2-5(369017), Krt2-8(25626), Krt2-8(25626)

Immunogen

cultured human epidermoid carcinoma cell line A-431.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse is suitable for the following applications:
  • Immunohistochemistry (formalin-fixed, paraffin-embedded sections)
  • Indirect immunofluorescence at a working dilution of 1:100 using formalin-fixed, paraffin-embedded human tissue sections.
  • Microarray

Biochem/physiol Actions

Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.
The antibody reacts with squamous, non-keratinized epithelium, transitional epithelium, pseudostratified epithelium, and myoepithelium.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Clase de almacenamiento

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Huan He et al.
The Journal of biological chemistry, 290(21), 13567-13577 (2015-04-09)
Squamous cell differentiation requires the coordinated activation and repression of genes specific to the differentiation process; disruption of this program accompanies malignant transformation of epithelium. The exploration of genes that control epidermal proliferation and terminal differentiation is vital to better
Helen M Rigden et al.
PloS one, 11(5), e0156009-e0156009 (2016-05-27)
To quantify the extent of squamous metaplasia in bronchial biopsies and relate it to the presence of chronic obstructive pulmonary disease (COPD), a smoking-related pathology. Bronchial biopsies (n = 15 in each group) from smokers with COPD GOLD stage1 and
S Spuler et al.
The American journal of pathology, 148(5), 1359-1365 (1996-05-01)
To study the possible role of thymomas and of extrathymomal thymic tissue in the development and maintenance of myasthenia gravis, we transplanted fragments of either tissue into SCID mice and monitored the production of anti-acetylcholine receptor antibodies in the recipients.
Debarchana Saha et al.
PloS one, 12(2), e0171084-e0171084 (2017-02-09)
Hemoglobin (Hb) is a major protein involved in transport of oxygen (O2). It consists of Hb-α and Hb-β subunits, which are normally expressed by cells of erythroid lineage. However, till recently, it was not known whether non-erythroid cells like vaginal
Aurélie Avril-Delplanque et al.
Stem cells (Dayton, Ohio), 23(7), 992-1001 (2005-07-27)
Airway epithelium stem cells have not yet been prospectively identified, but it is generally assumed that both secretory and basal cells have the capacity to divide and differentiate. Previously, we developed a test for progenitor cells of the human airway

Número de artículo de comercio global

SKUGTIN
C0791-100UL04061838030290

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