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Merck
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Documentos clave

B9684

Sigma-Aldrich

Anti-Brn3a antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-FLJ13449, Anti-OCT-T1, Anti-RDC1

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About This Item

Número MDL:
MFCD02262629
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

buffered aqueous solution

mol peso

antigen 42.9 kDa

reactividad de especies

human

reactividad de especies (predicha por homología)

mouse

técnicas

immunocytochemistry: 1:200-1:1000
immunohistochemistry (frozen sections): 1:200-1:1000
western blot: 1:200-1:1000

Nº de acceso UniProt

Q01851

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

human ... POU4F1(5457)
mouse ... Pou4f1(18996)
rat ... Pou4f1(114503)

Descripción general

Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.

Inmunógeno

POU4F1 / BRN3A antibody was raised against synthetic peptide (aa 141-157, AGGGGAHDGPGGGGGPG) corresponding to human Brn3a (BSA conjugated). Percent identity by BLAST analysis: Human (100%); Mouse (94%); Drosophila (82%).

Epitope
aa141-157

Forma física

Supplied in phosphate buffered saline, pH 7.4

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
SLBT5525
SLBT4491
SLBT1454
SLBS1543V
SLBQ0081V

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Brenna Krieger et al.
PloS one, 12(7), e0180091-e0180091 (2017-07-29)
The retina communicates with the brain using ≥30 parallel channels, each carried by axons of distinct types of retinal ganglion cells. In every mammalian retina one finds so-called "alpha" ganglion cells (αRGCs), identified by their large cell bodies, stout axons
Peter Stacey et al.
SLAS discovery : advancing life sciences R & D, 23(6), 585-596 (2018-03-17)
Screening against a disease-relevant phenotype to identify compounds that change the outcome of biological pathways, rather than just the activity of specific targets, offers an alternative approach to find modulators of disease characteristics. However, in pain research, use of in
RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury.
Seyed Hosseini Fin, et al.
Frontiers in Cellular Neuroscience, 17, 1156084-1156084 (2023)
Fuxin Shi et al.
The European journal of neuroscience, 26(11), 3016-3023 (2007-11-17)
In mammals, hair cells and auditory neurons lack the capacity to regenerate, and damage to either cell type can result in hearing loss. Replacement cells for regeneration could potentially be made by directed differentiation of human embryonic stem (hES) cells.
Hans Jürgen Wester et al.
Theranostics, 5(6), 618-630 (2015-04-01)
Chemokine ligand-receptor interactions play a pivotal role in cell attraction and cellular trafficking, both in normal tissue homeostasis and in disease. In cancer, chemokine receptor-4 (CXCR4) expression is an adverse prognostic factor. Early clinical studies suggest that targeting CXCR4 with

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