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AV02052

Sigma-Aldrich

Anti-TNFRSF18 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Anti-Tumor necrosis factor receptor superfamily, member 18

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

26 kDa

reactividad de especies

human

concentración

0.5 mg - 1 mg/mL

técnicas

immunohistochemistry: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... TNFRSF18(8784)

Descripción general

TNFRSF18 belongs to TNF receptor super family. It is a 228-amino acid type 1 transmembrane protein with a cysteine-rich extracellular domain.

Inmunógeno

Synthetic peptide directed towards the C terminal region of human TNFRSF18

Aplicación

Anti-TNFRSF18 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 2-4 μg/ml is suitable.

Acciones bioquímicas o fisiológicas

TNFRSF18 regulates cell death mediated by T cell receptors. It has important role in inflammatory responses that are involved in autoimmune disorders such as collagen-induced arthritis, experimental autoimmune encephalomyelitis and autoimmune gastritis.

Secuencia

Synthetic peptide located within the following region: LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV

Forma física

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Theresa Placke et al.
Clinical & developmental immunology, 2010, 239083-239083 (2010-10-12)
The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. Initially thought to be critically involved in governing functions of regulatory T cells, GITR and its ligand
T P Velavan et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 44(5), 418-420 (2011-03-30)
Parasites are accountable for driving diversity within immune gene families. We identified and investigated regulatory single nucleotide polymorphisms (SNPs) in the promoter regions of the tumor necrosis factor receptor superfamily member 18 (TNFRSF18) gene by direct sequencing in a group

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