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452M-9

Cytokeratin (CAM 5.2) Mouse Monoclonal Antibody

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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
CAM 5.2, monoclonal
Application:
IHC (p)
Citations:
5
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

CAM 5.2, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (452M-94), vial of 0.5 mL concentrate (452M-95), bottle of 1.0 mL predilute (452M-97), vial of 1.0 mL concentrate (452M-96), bottle of 7.0 mL predilute (452M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG2aκ

control

appendix, hepatocellular carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

General description

Anti-CAM 5.2 is a mouse monoclonal antibody that was generated by using the human colorectal carcinoma cell line HT24. Anti-CAM 5.2 reacts with cytokeratins 7 and 8, which are expressed in simple and glandular epithelia and transitional epithelium. Anti-CAM 5.2 reacts with most normal epithelium and with most carcinomas, including those arising in the lung, liver, pancreas, GI tract, breast, genitourinary system, female reproductive organs, and some endocrine organs.[1] This antibody can be used as an aid to identify epithelial differentiation in normal and neoplastic tissues.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

Cytokeratin (CAM 5.2) Positive Control Slides, Product No. 452S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo
300M-1335M-9303M-1
species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

clone

CAM 5.2, monoclonal

clone

OSCAR, monoclonal

clone

35betaH11, monoclonal

clone

AE3, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice


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Preguntas

  1. Are there any keratins present in CAM 5.2?

    1 respuesta
    1. The CAM 5.2 antibody is commonly used for cytokeratins 8 and, to a lesser extent, CK7, but not for cytokeratin 18 or 19 (Am J Clin Pathol 2010;133:514). It specifically targets low molecular weight cytokeratins.

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