113R-2

CD13 (EP117) Rabbit Monoclonal Primary Antibody

• Sinónimos: Aminopeptidase-N
• Código UNSPSC: 12352203

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP117, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (113R-24); vial of 0.1 mL concentrate Research Use Only (113R-24-RUO); vial of 0.5 mL concentrate (113R-25); vial of 1.0 mL concentrate (113R-26); vial of 1.0 mL concentrate Research Use Only (113R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (113R-27); vial of 7.0 mL pre-dilute ready-to-use (113R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO)
• fabricante / nombre comercial: Cell Marque^™
• concentración: 0.1-5 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotipo: IgG
• control: liver
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic, membranous
• Información sobre el gen: human ... ANPEP(290)

Descripción

Descripción general

CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.

In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.

Calidad

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Ligadura / enlace

CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

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Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable