Y0001718

Drospirenone for peak identification

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: Drospirenone, 6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, Dihydrospirorenone
• Fórmula empírica (notación de Hill): C₂₄H₃₀O₃
• Número CAS: 67392-87-4
• Peso molecular: 366.49
• NACRES: NA.24
• PubChem Substance ID: 329830800
• UNSPSC Code: 41116107
• MDL number: MFCD00867350
• eCl@ss: 25140904

Propiedades

• grade: pharmaceutical primary standard
• API family: drospirenone
• manufacturer/tradename: EDQM
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[C@]12CCC(=O)C=C1[C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@@]5(C)[C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7
• InChI: 1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
• InChI key: METQSPRSQINEEU-HXCATZOESA-N
• Gene Information: human ... NR3C2(4306), PGR(5241)

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Drospirenone for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Drospirenone is a fourth-generation progestin that has antimineralocorticoid, and antiandrogenic activity in addition to potent progestogenic activity. In two recent studies drospirenone appeared to double the risk of venous thromboembolism compared to levonorgestrel, although other studies found little added risk.

Fourth-generation progestin; contraceptive

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de advertencia: Danger
• Códigos de peligro: H351,H360FD
• Indicaciones de precaución: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Carc. 2 - Repr. 1A
• Punto de inflamación (°F): No data available
• Punto de inflamación (°C): No data available