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PHR1154

Supelco

Tributyl citrate

Pharmaceutical Secondary Standard; Certified Reference Material

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About This Item

Fórmula empírica (notación de Hill):
C18H32O7
Número de CAS:
77-94-1
Peso molecular:
360.44
Beilstein:
1806072
Número CE:
201-071-2
Número MDL:
MFCD00027217
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329823172
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

300

Agency

traceable to USP 1680608

familia API

tributyl acetylcitrate

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

índice de refracción

n20/D 1.445

densidad

1.043 g/mL at 20 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

CCCCOC(=O)CC(O)(CC(=O)OCCCC)C(=O)OCCCC

InChI

1S/C18H32O7/c1-4-7-10-23-15(19)13-18(22,17(21)25-12-9-6-3)14-16(20)24-11-8-5-2/h22H,4-14H2,1-3H3

Clave InChI

ZFOZVQLOBQUTQQ-UHFFFAOYSA-N

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Descripción general

Tributyl citrate is an ester of citric acid. It is used to plasticize polymers for coating solid drug dosage forms, tablets and capsules.


Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA8989 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Ethyl p-toluenesulfonate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

68383

Ethyl p-toluenesulfonate

Triethyl citrate ≥99%, FCC, FG

Sigma-Aldrich

W308307

Triethyl citrate

Triethyl citrate ≥98.0% (GC)

Sigma-Aldrich

27500

Triethyl citrate

Carbon, mesoporous hydrophilic pore surface

Sigma-Aldrich

702110

Carbon, mesoporous

Handbook of Pharmaceutical Excipients, 1 (2006)
Eva Roblegg et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(3), 635-645 (2011-08-02)
The objective of this study was the development of retarded release pellets using vegetable calcium stearate (CaSt) as a thermoplastic excipient. The matrix carrier was hot melt extruded and pelletized with a hot-strand cutter in a one step continuous process.
Bernadette Pretzl et al.
Journal of clinical periodontology, 36(4), 349-356 (2009-05-12)
Evaluation of the 10-year results after GTR-therapy of infrabony defects using two bioabsorbable barriers in a randomized-controlled clinical trial. In 15 patients with periodontitis, 15 pairs of infrabony defects were treated. For each patient, one defect received a polydioxanon (test:
W Korsatko et al.
Die Pharmazie, 38(9), 608-611 (1983-09-01)
Matrix type tablets containing 7-hydroxyethyltheophylline, L-noradrenaline and L-isoproterenol were coated with Eudragit RS 100 film containing different concentrations of 1,2-propyleneglycol (PG) and tributylcitrate (TBC) as hydrophylic and lipophilic softeners, respectively, to effect a controlled liberation of the substances. In-vitro and
Werner Schroth et al.
Marine biotechnology (New York, N.Y.), 7(5), 449-461 (2005-06-25)
We describe a strategy that identifies molecular biomarkers and links the study of abiotic stress to evolutionary history. By utilizing the moon jellyfish Aurelia spp. as a model, we identified genes differentially regulated in response to the chemical stressor tributyltin
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