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Merck

69545

Supelco

Kaempferide

analytical standard

Sinónimos:

3,5,7-Trihydroxy-4′-methoxyflavone, KF, 4′-Methoxy-3,5,7-trihydroxyflavone

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About This Item

Fórmula empírica (notación de Hill):
C16H12O6
Número de CAS:
Peso molecular:
300.26
Beilstein:
305378
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

Análisis

≥99.0% (HPLC)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

food and beverages

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3

Clave InChI

SQFSKOYWJBQGKQ-UHFFFAOYSA-N

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Descripción general

Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.

Aplicación

Kaempferide may be used as an analytical reference standard for the quantification of the analyte in propolis and traditional Chinese medicine Zuo Gui Wan using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Otras notas

This compound is commonly found in plants of the genus: arnica silybum

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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A combined HPLC-PDA and HPLC-MS method for quantitative and qualitative analysis of 10 major constituents in the traditional Chinese medicine Zuo Gui Wan
Liang X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 931-936 (2009)
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific Reports, 7(1) (2017)
Selective analysis of phenolic compounds in propolis by HPLC?MS/MS
Medana C, et al.
Phytochemical Analysis, 19(1), 32-39 (2008)
Ehab Ghazy et al.
European journal of medicinal chemistry, 200, 112338-112338 (2020-06-05)
Histone modifying proteins, specifically histone deacetylases (HDACs) and bromodomains, have emerged as novel promising targets for anticancer therapy. In the current work, based on available crystal structures and docking studies, we designed dual inhibitors of both HDAC6/8 and the bromodomain
Cuiping Zhang et al.
Journal of food science, 82(7), 1602-1607 (2017-06-01)
Brazilian green propolis is known as an appreciable natural antioxidant with abundant polyphenolic compounds. For quality control, a fingerprint-efficacy study of Brazilian green propolis was carried out in this work. Chemical fingerprints of Brazilian green propolis from 22 different sources

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