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67805

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Idevenone

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C19H30O5
Número de CAS:
58186-27-9
Peso molecular:
338.44
Número MDL:
MFCD00274552
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329760681
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Análisis

≥97.0% (HPLC)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)
veterinary

formato

neat

cadena SMILES

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

Clave InChI

JGPMMRGNQUBGND-UHFFFAOYSA-N

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Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCK6000
BCCK5999
BCCD5091
BCCC1147
BCCB8933

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Patricia Farris
Dermatologic therapy, 20(5), 322-329 (2007-11-30)
The use of topical antioxidants is gaining favor among dermatologists because of their broad biologic activity. Many are not only antioxidants but also have antiinflammatory and anticarcinogenic activities. Thus for dermatologists these cosmeceuticals have many potential applications. In general, topical
H Morimoto
Die Naturwissenschaften, 76(5), 200-205 (1989-05-01)
Syntheses of some metabolites of ubiquinone and of related compounds are described. Idebenone (QSA-10), a methyl-dimethoxy-benzoquinone bearing an omega-hydroxydecyl side chain in 3-position, restored the oxidation of succinate and of NADH in ubiquinone-depleted mitochondrial preparations and showed a stabilizing effect
Thomas Meier et al.
Journal of neurology, 256 Suppl 1, 25-30 (2009-04-11)
This paper reviews the history and pre-clinical development of idebenone and summarises the results of clinical studies, published from 1999 to 2008, on the use of idebenone in the treatment of patients with Friedreich ataxia (FRDA). As a benzoquinone that
Jörg B Schulz et al.
Journal of neurology, 256 Suppl 1, 42-45 (2009-04-11)
Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia. However, the effects of idebenone on neurological function have not been reliably determined in these studies; when
[The use of idebenone (noben) in neurological practice].
I V Damulin
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 106(11), 66-71 (2006-12-21)
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