383376

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

• Sinónimos: Antimony potassium tartrate trihydrate, Tartar emetic
• Fórmula empírica (notación de Hill): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• Número de CAS: 28300-74-5
• Peso molecular: 667.87
• Número CE: 234-293-3
• Número MDL: MFCD00167056
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24863959
• NACRES: NA.21

Propiedades

• grado: ACS reagent
• Nivel de calidad: 200
• Análisis: ≥99%; 99.0-103.0%
• formulario: powder
• impurezas: ≤0.020 meq/g Titr. acid or base
• pérdida: ≤2.7% loss on drying
• mp: ≥300 °C (lit.)
• solubilidad: water: soluble
• trazas de catión: As: ≤0.015%
• cadena SMILES: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
• Clave InChI: WBTCZEPSIIFINA-UHFFFAOYSA-J

Descripción

Descripción general

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Aplicación

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H301,H315,H317,H332,H411
• Consejos de prudencia: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Clasificaciones de peligro: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves