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Merck

18571

Supelco

Amentoflavone

analytical standard

Sinónimos:

Didemethyl-ginkgetin, I3′,II8-Biapigenin, Tridemethylsciadopitysin

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About This Item

Fórmula empírica (notación de Hill):
C30H18O10
Número de CAS:
Peso molecular:
538.46
Beilstein:
380244
Número MDL:
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

Análisis

≥98.0% (HPLC)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

food and beverages

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)c(c3O2)-c4cc(ccc4O)C5=CC(=O)c6c(O)cc(O)cc6O5

InChI

1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H

Clave InChI

YUSWMAULDXZHPY-UHFFFAOYSA-N

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Categorías relacionadas

Descripción general

Amentoflavone is a flavonoid which is used as an antiviral agent.

Aplicación

It was used as a standard during HPLC analysis done for separating chemical components.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Otras notas

This compound is commonly found in plants of the genus: ginkgo hypericum

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

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Yuchi Zhang et al.
Journal of separation science, 33(17-18), 2743-2748 (2010-08-24)
A novel gradient elution was efficiently utilized for the separation of the chemical components with a wide range of polarity from the mixed extract of the Chinese medicinal herb Apocynum venetum or mixed standards by high-speed counter-current chromatography. Three sets
S C Ma et al.
Biological & pharmaceutical bulletin, 24(3), 311-312 (2001-03-21)
Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 microg/ml. The contents of amentoflavone in nine species of Selaginella were
Hans Michler et al.
Phytochemical analysis : PCA, 22(1), 42-50 (2010-09-08)
Biflavones of Hypericum perforatum L. are bioactive compounds used in the treatment of inflammation and depression. Determination of amentoflavone and biapigenin from blood is challenging owing to their similar structures and low concentrations. To develop a rapid, sensitive and accurate
K S Siveen et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 30(4), 301-309 (2011-12-21)
Flavanoids are polyphenolic compounds that are found in fruits and vegetables and have diverse, beneficial biochemical and antioxidant effects. The objective of this study was to assess the effect of amentoflavone, a biflavanoid isolated from Biophytum sensitivum, on cell cycling
Ismail O Ishola et al.
Journal of ethnopharmacology, 142(2), 383-389 (2012-05-23)
Cnestis ferruginea (CF) Vahl ex DC (Connaraceae) is a shrub widely used in Traditional African Medicine (TAM) for the treatment of various painful and inflammatory conditions. To isolate the active pharmacological constituents responsible for the anti-inflammatory and antinociceptive properties of

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