131164

Indigo carmine

certified by the Biological Stain Commission, Dye content 85 %

• Sinónimos: Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine
• Fórmula empírica (notación de Hill): C₁₆H₈N₂Na₂O₈S₂
• Número de CAS: 860-22-0
• Peso molecular: 466.35
• Número de índice de color: 73015
• Beilstein: 4103904
• Número CE: 212-728-8
• Número MDL: MFCD00005723
• Código UNSPSC: 12171500
• ID de la sustancia en PubChem: 24847997
• NACRES: NA.47

Propiedades

• grado: certified by the Biological Stain Commission
• Nivel de calidad: 200
• Análisis: >85.0% (HPLC)
• formulario: solid
• composición: Dye content, 85%
• color: dark blue to very dark blue
• pH: 3.87 (30 °C, 7.14 g/L)
• mp: ≥340 °C
• densidad: 0.71 g/cm³ at 29 °C
• λmáx.: 608 nm
• εmax: 20,000 at 250-256 nm in water at 0.01 g/L; 29500 at 284-290 nm in water at 0.01 g/L
• aplicaciones: diagnostic assay manufacturing; hematology; histology
• temp. de almacenamiento: room temp
• cadena SMILES: [Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
• InChI: 1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
• Clave InChI: KHLVKKOJDHCJMG-QDBORUFSSA-L

Descripción

Aplicación

Indigo carmine has been used to investigate its effects on ozone production by neutrophils.

Acciones bioquímicas o fisiológicas

Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

Idoneidad

Used as a collagen stain and in procedures using red nuclear stains.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves