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10784

Sigma-Aldrich

Antipyrine

tested according to Ph. Eur.

Sinónimos:

Phenazonum, 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one, Phenazone

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About This Item

Fórmula empírica (notación de Hill):
C11H12N2O
Número de CAS:
60-80-0
Peso molecular:
188.23
Beilstein:
157775
Número CE:
200-486-6
Número MDL:
MFCD00003146
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329749157
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

Nivel de calidad

100

formulario

crystals and lumps
powder

mp

109-111 °C (lit.)

solubilidad

H2O: soluble 1 gm in less than 1ml
alcohol: soluble 1 gm in 1.3 ml
chloroform: soluble 1 gm in 1 ml
diethyl ether: soluble 1 gm in 43 ml

aplicaciones

pharmaceutical (small molecule)

cadena SMILES

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

Clave InChI

VEQOALNAAJBPNY-UHFFFAOYSA-N

Información sobre el gen

human ... PTGS1(5742)

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Aplicación

Antipyrine has been used for immunoblotting. It has also been used as an internal reference marker for studying the transport characteristics of platinum-containing drug, cisplatin in the human placenta in vitro.

Acciones bioquímicas o fisiológicas

Antipyrine also referred to as phenazone or phenazonum is an anti-inflammatory agent that possesses analgesic, antipyretic and platelet-inhibitory actions.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
BCCH7205
BCCG5616
BCCG0014
BCCD7833
BCCC8539

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Eyad Al-Saleh et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 21(10), 726-731 (2008-11-18)
Platinum-containing drugs are used extensively in the treatment of various malignancies in humans. Data are scarce on the maternal-fetal transport characteristics in humans of one such widely used drug, cisplatin, and this prompted us to study its transport characteristics in
E Girbal-Neuhauser et al.
Journal of immunology (Baltimore, Md. : 1950), 162(1), 585-594 (1999-01-14)
Antifilaggrin autoantibodies (AFA) are a population of IgG autoantibodies associated to rheumatoid arthritis (RA), which includes the so-called "antikeratin" Abs and antiperinuclear factor. AFA are the most specific serological markers of RA. We previously showed that they recognize human epidermal
Gro Klitgaard Povlsen et al.
BMC neuroscience, 14, 34-34 (2013-03-19)
Upregulation of vasoconstrictor receptors in cerebral arteries, including endothelin B (ETB) and 5-hydroxytryptamine 1B (5-HT(1B)) receptors, has been suggested to contribute to delayed cerebral ischemia, a feared complication after subarachnoid hemorrhage (SAH). This receptor upregulation has been shown to be
Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)
Antipyrine as a model drug to study hepatic drug-metabolizing capacity.
H E Poulsen et al.
Journal of hepatology, 6(3), 374-382 (1988-06-01)
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