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05292

Sigma-Aldrich

Spermidine 0.1 M solution

Sinónimos:

Spermidine solution, Additive Screening Solution 30/Kit-No 78374

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About This Item

Número de CAS:
124-20-9
Número MDL:
MFCD00008229
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329747679
NACRES:
NA.32

Nivel de calidad

100

densidad

1.00 g/mL at 20 °C

temp. de almacenamiento

2-8°C

cadena SMILES

NCCCCNCCCN

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

Clave InChI

ATHGHQPFGPMSJY-UHFFFAOYSA-N

Información sobre el gen

mouse ... Odc1(18263)
rat ... Ppm1a(24666)

Acciones bioquímicas o fisiológicas

Spermidine is a naturally occurring polyamine. It is associated with various cellular functions. It is responsible for the condensation and aggregation of DNA in aqueous solution. Spermidine is known to extend lifespan via epigenetic modifications, induction of cell death and inhibition of necrosis.
Spermidine 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Faceshields, Gloves, Goggles

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Certificados de análisis (COA)

Lot/Batch Number
BCCK8108
BCCJ2613
BCCG2475
BCCD1963
BCBS0033V

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Induction of autophagy by spermidine promotes longevity.
Eisenberg T et al.
Nature Cell Biology, 11, 1305-1305 (2009)
53rd National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB) and National Meeting of Chemistry of Biological Systems ? Italian Chemical Society (SCI - Section CSB) (2008)
Satyanarayana U
Biochemistry (2014)
Marjorie Catala et al.
Bio-protocol, 10(12), e3646-e3646 (2021-03-05)
Transfer RNAs (tRNAs) are heavily decorated with post-transcriptional modifications during their biosynthesis. To fulfil their functions within cells, tRNAs undergo a tightly controlled biogenesis process leading to the formation of mature tRNAs. In addition, functions of tRNAs are often modulated
Maria Anna Bauer et al.
Cell cycle (Georgetown, Tex.), 12(2), 346-352 (2012-12-21)
Spermidine is a naturally occurring polyamine involved in multiple biological processes, including DNA metabolism, autophagy and aging. Like other polyamines, spermidine is also indispensable for successful reproduction at several stages. However, a direct influence on the actual fertilization process, i.e.
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