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03930590

Protocatechuic acid

primary reference standard

Sinónimos:

3,4-Dihydroxybenzoic acid, Protocatechuic acid

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About This Item

Fórmula lineal:
(HO)2C6H3CO2H
Número de CAS:
99-50-3
Peso molecular:
154.12
Beilstein:
1448841
Número CE:
202-760-0
Número MDL:
MFCD00002509
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
329747840
NACRES:
NA.24

grado

primary reference standard

caducidad

limited shelf life, expiry date on the label

fabricante / nombre comercial

HWI

mp

197-200 °C (dec.) (lit.)

aplicaciones

food and beverages

cadena SMILES

OC(=O)c1ccc(O)c(O)c1

InChI

1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)

Clave InChI

YQUVCSBJEUQKSH-UHFFFAOYSA-N

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Descripción general

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Protocatechuic acid belongs to the class of polyphenolic compounds, which can be generally isolated from the dried flower of roselle. It can serve as a potential candidate possessing anticancer property, which can be involved in suppressing the growth of human promyelocytic leukemia HL-60 cells.

Aplicación

Reference Standard in the analysis of herbal medicinal products

Acciones bioquímicas o fisiológicas

Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.

Otras notas

This compound is commonly found in plants of the genus: allium carum cinnamomum curcuma ginkgo humulus melissa pimpinella thymus

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
HWI03166-1
HWI03166
HWI02119-2
HWI02119-1
HWI02119

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Sigma-Aldrich

D7927

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Syringic acid ≥95% (HPLC)

Sigma-Aldrich

S6881

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Caffeic acid ≥98.0% (HPLC)

Sigma-Aldrich

C0625

Caffeic acid

Syringic acid analytical standard

Supelco

63627

Syringic acid

In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved
Kaarjel K Narayanasamy et al.
Frontiers in synaptic neuroscience, 13, 671288-671288 (2021-07-06)
The development of super-resolution microscopy (SRM) has widened our understanding of biomolecular structure and function in biological materials. Imaging multiple targets within a single area would elucidate their spatial localization relative to the cell matrix and neighboring biomolecules, revealing multi-protein
Dongliang Wang et al.
Circulation research, 111(8), 967-981 (2012-07-24)
We and others have demonstrated that anthocyanins have antiatherogenic capability. Because intact anthocyanins are absorbed very poorly, the low level of circulating parent anthocyanins may not fully account for their beneficial effect. We found recently that protocatechuic acid (PCA), a
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