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02191

Sigma-Aldrich

Adipic acid dihydrazide

purum, ≥97.0% (NT)

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About This Item

Fórmula lineal:
NH2NHCO(CH2)4CONHNH2
Número de CAS:
1071-93-8
Peso molecular:
174.20
Beilstein:
973863
Número CE:
213-999-5
Número MDL:
MFCD00007614
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329747401

grado

purum

Ensayo

≥97.0% (NT)

mp

180-182 °C (lit.)
180-182 °C

cadena SMILES

NNC(=O)CCCCC(=O)NN

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

Clave InChI

IBVAQQYNSHJXBV-UHFFFAOYSA-N

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Aplicación

Adipic acid dihydrazide can be used to study chemical synthesis, organic building blocks, carbonyl compounds and hydrazides. Adipic acid dihydrazide has been used in a study to show that diphtheria toxoid can be successfully employed as a carrier protein for conjugation with Salmonella O-specific polysaccharides and play an important role in facilitating adequate immune response in typhoid fever vaccines. Adipic acid dihydrazide has also been used in a study to assess the activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana.

Otras notas

Bifunctional linker employed for the immobilization of carbohydrates, e.g. to MMAC resins (methyl vinyl ether, maleic anhydride co-polymer)

sustituido por

Referencia del producto
Descripción
Precios

A0638

Adipic acid dihydrazide, ≥98% (titration)

Pictogramas

Environment
GHS09

Frases de peligro

H411

Consejos de prudencia

P273 - P391 - P501

Clasificaciones de peligro

Aquatic Chronic 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

302.0 °F - closed cup

Punto de inflamabilidad (°C)

150 °C - closed cup

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number

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A Satoh et al.
Analytical biochemistry, 275(2), 231-235 (1999-12-20)
The immobilization of carbohydrates for solid-phase assays, including enzyme-linked immunosorbent assay (ELISA), is difficult because they are hydrophilic. We developed four new methods for the immobilization of oligosaccharides. ELISA plates were first coated with methyl vinyl ether-maleic anhydride copolymer (MMAC)
A Satoh et al.
Analytical biochemistry, 260(1), 96-102 (1998-07-02)
We have previously reported a method to immobilize protein ligands on microtiter plates coated with methyl vinyl ether-maleic anhydride copolymer (MMAC) [Isosaki, K., et al. (1992) J. Chromatogr. 597, 123-128]. In this study, we improved the MMAC method to efficiently
So Jung An et al.
Vaccine, 29(44), 7618-7623 (2011-08-17)
In this study it was demonstrated that the immunogenicity of Vi polysaccharide-diphtheria toxoid conjugates was related to the physical and chemical structure of the conjugate. Conjugates were prepared in two steps, firstly binding adipic acid dihydrazide (ADH) spacer molecules to
Tulsidas G Shrivastav
Journal of immunoassay & immunochemistry, 25(3), 295-304 (2004-10-06)
Peroxidase hydrazides were prepared by conjugating horseradish peroxidase (HRP) to adipic acid dihydrazide (ADH) by carbodiimide or periodate oxidation method. The resulting HRP hydrazides (ADH-HRP) were conjugated to cortisol-21-hemisuccinate (cortisol-21-HS) by forming diimide bonds using the N-hydroxysuccinimide (NHS) carbodiimide mediated
Yu-Chun Chen et al.
Acta biomaterialia, 9(2), 5181-5193 (2012-10-09)
Encapsulation of nucleus pulposus (NP) cells within in situ forming hydrogels is a novel biological treatment for early stage intervertebral disc degeneration. The procedure aims to prolong the life of the degenerating discs and to regenerate damaged tissue. In this
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