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01700

Sigma-Aldrich

Acrilamida

purum, ≥98.0% (GC)

Sinónimos:

2-Propenamida, Amida del ácido acrílico

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About This Item

Fórmula lineal:
CH2=CHCONH2
Número de CAS:
79-06-1
Peso molecular:
71.08
Beilstein:
605349
Número CE:
201-173-7
Número MDL:
MFCD00008032
Código UNSPSC:
41105319
eCl@ss:
39031205
ID de la sustancia en PubChem:
329747349
NACRES:
NB.22

densidad de vapor

2.45 (vs air)

Nivel de calidad

200

presión de vapor

0.03 mmHg ( 40 °C)

grado

purum

Análisis

≥98.0% (GC)

bp

125 °C/25 mmHg (lit.)

mp

81-87 °C
82-86 °C (lit.)

solubilidad

water: soluble 200 g/L at 20 °C

temp. de almacenamiento

room temp

cadena SMILES

NC(=O)C=C

InChI

1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)

Clave InChI

HRPVXLWXLXDGHG-UHFFFAOYSA-N

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Aplicación

Acrylamide has been used for preparing slab gel gradients for polyacrylamide gel electrophoresis (PAGE).

Acciones bioquímicas o fisiológicas

Acrylamide is a reactive, water soluble vinyl monomer. It causes a decrease in the number of neuritis per cell as well as reduces the rate of protein synthesis.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral

Órganos de actuación

Peripheral nervous system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

280.4 °F - closed cup

Punto de inflamabilidad (°C)

138 °C - closed cup

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
BCCM2995
BCCL7033
BCCK3678
BCCH3077
BCCF6792

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M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Janneke G F Hogervorst et al.
Carcinogenesis, 35(5), 1032-1038 (2014-01-09)
Acrylamide, a probable human carcinogen, is present in heat-treated carbohydrate-rich foods. Epidemiological studies have not shown a clear association between acrylamide intake and colorectal cancer (CRC) risk. This may be due to the molecular heterogeneity in colorectal tumors, which was
Rusty L Montgomery et al.
EMBO molecular medicine, 6(10), 1347-1356 (2014-09-23)
Over the last decade, great enthusiasm has evolved for microRNA (miRNA) therapeutics. Part of the excitement stems from the fact that a miRNA often regulates numerous related mRNAs. As such, modulation of a single miRNA allows for parallel regulation of
Franco Pedreschi et al.
Journal of the science of food and agriculture, 94(1), 9-20 (2013-08-14)
Acrylamide (AA) is known as a neurotoxin in humans and it is classified as a probable human carcinogen by the International Agency of Research on Cancer. AA is produced as by-product of the Maillard reaction in starchy foods processed at
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