MECY2MAG73KPXBK

MILLIPLEX^® Mouse Cytokine/Chemokine Magnetic Bead Panel II Premix Space Saver (Bulk) Packaging

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

• Código UNSPSC: 12161503
• eCl@ss: 32161000
• NACRES: NA.47

Propiedades

• Nivel de calidad: 200
• reactividad de especies: mouse
• fabricante / nombre comercial: Milliplex^®
• assay range: standard curve range: 1-5,000 pg/mL; (IFNγ); standard curve range: 12-50,000 pg/mL; (Exodus-2/CCL21/6Ckine); standard curve range: 12-50,000 pg/mL; (IFNβ1); standard curve range: 12-50,000 pg/mL; (IL-11); standard curve range: 12-50,000 pg/mL; (IL-20); standard curve range: 12-50,000 pg/mL; (MIP-3β/CCL19); standard curve range: 2-10,000 pg/mL; (IL-16); standard curve range: 2-10,000 pg/mL; (MCP-5/CCL12); standard curve range: 2-10,000 pg/mL; (MDC/CCL22); standard curve range: 2-10,000 pg/mL; (MIP-3α/CCL20); standard curve range: 2-10,000 pg/mL; (TARC/CCL17); standard curve range: 24-100,000 pg/mL; (Fractalkine/CX3CL1); standard curve range: 24-100,000 pg/mL; (IL-17A/F); standard curve range: 5-20,000 pg/mL; (Erythropoietin (EPO))
• técnicas: multiplexing: suitable
• compatibilidad: configured for Premixed
• método de detección: fluorometric (Luminex xMAP)
• Condiciones de envío: wet ice

Descripción

Descripción general

Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. A generic term, “cytokines” includes myokines (produced by muscle cells), lymphokines (produced by activated Th cells), interleukins (acting as mediators between T cells) and chemokines (responsible for T-cell migration). One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process. In addition, the mouse model and mouse-to-human translational studies provide data essential to understanding the role of cytokines and immune response in both normal and disease states.

The MILLIPLEX^® Mouse Cytokine/Chemokine Bead Panel II Premixed 14 Plex, contains all the components necessary to measure the following 14 biomarkers using Luminex^® xMAP^® technology: Erythropoietin (EPO), Exodus-2/CCL21/6Ckine, Fractalkine/CX3CL1, IFNβ1, IFNγ, IL-11, IL-16, IL-17A/F, IL-20, MCP-5/CCL12, MDC/CCL22, MIP-3α/CCL20, MIP-3β/CCL19, TARC /CCL17. The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 serum, plasma, or cell/tissue culture samples in duplicate.

Panel Type: Cytokines/Chemokines

Aplicación

• Analytes: Erythropoietin (EPO), Exodus-2, Fractalkine/CX3CL1, IFNβ1, IFNγ, IL-11, IL-16, IL-17A/F, IL-20, MCP-5/CCL12, MDC (CCL22), MIP-3α/CCL20, MIP-3β/CCL19, TARC/CCL17.
• Recommended Sample type: serum, plasma and cell culture
• Recommended Sample dilution: 1:2 dilution of serum and plasma. Tissue culture supernatant may require a dilution with an appropriate control medium
• Assay Run Time: overnight or one day
• Research Category: Inflammation & Immunology

Otras notas

Please contact Technical Service for linearity of dilution.

Sensitivity: Refer to kit protocol for sensitivities of individual cytokines/chemokines.

Información legal

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H302 + H332,H311,H317,H319,H411
• Consejos de prudencia: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3