MABT25

Anti-Myosin 2 Antibody, clone 5B11.1

clone 5B11.1, from mouse

• Sinónimos: Myosin-2, Myosin heavy chain 2, Myosin heavy chain 2a, MyHC-2a, Myosin heavy chain Iia, MyHC-Iia, Myosin heavy chain, skeletal muscle, adult 2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 5B11.1, monoclonal
• reactividad de especies: mouse, human, rat
• técnicas: immunohistochemistry: suitable; western blot: suitable
• isotipo: IgG3κ
• Nº de acceso NCBI: NP_060004
• Nº de acceso UniProt: Q9UKX2
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MYH2(4620)

Descripción

Descripción general

Myosin is a hexameric protein consisting of two heavy chains including Myosin-2 (MYH2), two regulatory light chains, and two alkali light chains. The myosin-2 heavy chain interacts with the actin cytoskeleton and mediates muscle contractility in eukaryotic cells. Defects in myosin-2 result in inclusion body myopathy type 3.

Inmunógeno

KLH-conjugated linear peptide corresponding to mouse Myosin 2.

Aplicación

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

This Anti-Myosin 2 Antibody, clone 5B11.1 is validated for use in Western Blotting, IHC for the detection of Myosin 2.

Western Blot Analysis: 0.5 µg/mL from a representative lot detected Myosin-2 in L6 cell lysate (Myosin may be observed as a smear in some cell lysates).

Western Blot Analysis: A representative lot detected Myosin-2 in mouse heart cell cytosolic extracts.

Calidad

Evaluated by Immunohistochemistry in human cardiac muscle tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Myosin-2 in human cardiac muscle tissue.

Descripción de destino

~220 kDa observed

Forma física

Format: Purified

Purified mouse monoclonal IgG3κ in buffer containing PBS with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human cardiac muscle tissue

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable