MABF116

Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157

clone Ham25-1157, from hamster

• Sinónimos: T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, HMT3-2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: hamster
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: Ham25-1157, monoclonal
• reactividad de especies: human
• reactividad de especies (predicha por homología): mouse (based on 100% sequence homology)
• técnicas: flow cytometry: suitable
• Nº de acceso NCBI: NP_033980
• Nº de acceso UniProt: P11942
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD3G(917)

Descripción

Descripción general

The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains: gamma, delta, epsilon and zeta. CD3 is first detectable in early thymocytes and one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, it is detected on the cell surface. The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies.

Especificidad

This antibody recognizes CD3 gamma delta.

Inmunógeno

Purified protein corresponding to mouse CD3 gamma delta.

Aplicación

Anti-CD3 gamma delta (HMT3-2) Antibody, clone Ham25-1157 detects level of CD3 gamma delta (HMT3-2) & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Calidad

Evaluated by Flow Cytometry in Jurkat cells.

Flow Cytometry Analysis: 2.5 µg/mL of this antibody detected CD3 gamma delta in 1X10E5 Jurkat cells.

Descripción de destino

21 kDa calculated

Forma física

Format: Purified

Protein G Purified

Purified armenian hamster monoclonal IgG2bλ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Jurkat cells

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable