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MAB858-4

Sigma-Aldrich

Anti-RSV Antibody, blend, clones 133-1H, 131-2G, and 130-12H

ascites fluid, Chemicon®, from mouse

Sinónimos:

RSV

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

ascites fluid

tipo de anticuerpo

primary antibodies

clon

130-12H, monoclonal
131-2G, monoclonal
133-1H, monoclonal

reactividad de especies

human

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunofluorescence: suitable

isotipo

IgG

Condiciones de envío

wet ice

Descripción general

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

Especificidad

Blend of all RSV specifications of MAB858-1, 2 and 3. Recognizes the fusion, G, and nuclear protein of both A and B strains.

Inmunógeno

A2

Aplicación

Anti-RSV Antibody, blend, clones 133-1H, 131-2G & 130-12H is an antibody against Respiratory Syncytial Virus for use in IF, ELISA.
ELISA at 1:800+

Indirect Immunofluorescence at 1:100-200+ (fresh frozen tissue sections)

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Forma física

Liquid ascites fluid.
Unpurified

Almacenamiento y estabilidad

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
RSV Control Slides, Catalogue Number 5012-5

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Tiina Talts et al.
Microbiology spectrum, 12(4), e0306723-e0306723 (2024-02-27)
Prevention of respiratory syncytial virus (RSV) infection is now a global health priority, with a long-acting monoclonal antibody and two RSV vaccines recently licenced for clinical use. Most licenced and candidate interventions target the RSV fusion (RSV-F) protein. New interventions
Talita Bianca Gagliardi et al.
Intervirology, 60(1-2), 56-60 (2017-09-05)
Syncytia formation is the hallmark of the cytopathic effect caused by human respiratory syncytial virus (HRSV), which is the most important viral respiratory pathogen in children. This article reports methodological improvements in primary HRSV isolation and the importance of syncytia
John P DeVincenzo et al.
The Journal of infectious diseases, 190(5), 975-978 (2004-08-06)
Premature infants and those with chronic lung disease or congenital heart disease are at high risk of severe respiratory syncytial virus (RSV) disease. Palivizumab (Synagis), a humanized anti-RSV monoclonal antibody, has been used extensively since 1998 to prevent severe RSV
Ziyin Wang et al.
Mucosal immunology, 17(2), 272-287 (2024-02-22)
Respiratory viral infections remain a major cause of hospitalization and death worldwide. Patients with respiratory infections often lose weight. While acute weight loss is speculated to be a tolerance mechanism to limit pathogen growth, severe weight loss following infection can
Hayat Caidi et al.
Methods in molecular biology (Clifton, N.J.), 1442, 13-32 (2016-07-29)
Defective interfering viral particles have been reported as important determinants of the course of viral infection, and they can markedly temper the virulence of the infection. Here, we describe a simple method, based on limiting dilution, for the removal of

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