MAB4356A4

Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor^™ 488 conjugate

clone 6C1.2, from mouse, ALEXA FLUOR^™ 488

• Sinónimos: Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: ALEXA FLUOR^™ 488
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 6C1.2, monoclonal
• reactividad de especies: mouse
• técnicas: immunocytochemistry: suitable
• Nº de acceso NCBI: NP_082891
• Nº de acceso UniProt: Q9CWH0
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Dppa2(73703)

Descripción

Descripción general

DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.

Inmunógeno

recombinant protein corresponding to mouse DPPA-2.

Aplicación

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

This Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2.

Calidad

Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).

Descripción de destino

~30 kDa observed

Forma física

Protein G Purified

Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análisis

Control
Mouse Embryonic Stem Cells (SCR012).

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

ALEXA FLUOR is a trademark of Life Technologies

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable