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MAB396

Sigma-Aldrich

Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11

clone 3A11, Chemicon®, from mouse

Sinónimos:

GluR2/4

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

3A11, monoclonal

reactividad de especies

monkey, human, rat

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable
western blot: suitable

isotipo

IgG2a

Nº de acceso NCBI

NM_000839.2

Nº de acceso UniProt

Q14416
Q14833

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... GRIA2(2891)
rat ... Gria2(29627)
rhesus monkey ... Gria2(574344)

Especificidad

Glutamate Receptor 2 (GluR2) by Western blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.

Inmunógeno

Recombinant fusion protein TrpE-GluR2

Aplicación

Detect Glutamate Receptor 2 & 4 using this Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 validated for use in ELISA, IC, IH, IP, RIA & WB.
Immunohistochemistry on 4% paraformaldehyde fixed

tissue: 1:500-1,000

Immunocytochemistry

ELISA

RIA

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Forma física

Format: Purified
Purified immunoglobulin. Liquid in PBS, no preservative.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up 12 months. Avoid repeated freeze/thaw cycles.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sheng Chen et al.
Journal of neuroscience research, 81(4), 522-529 (2005-06-11)
Lipid rafts are specialized plasma membrane microdomains enriched in cholesterol and sphingolipids that serve as major assembly and sorting platforms for signal transduction complexes. Constitutively expressed heat shock proteins Hsp90, Hsc70, Hsp60, and Hsp40 and a range of neurotransmitter receptors
Dannis G van Vuurden et al.
PloS one, 4(6), e5953-e5953 (2009-06-19)
Glioblastoma multiforme (GBM) cells secrete large amounts of glutamate that can trigger AMPA-type glutamate receptors (AMPARs). This commonly results in Na(+) and Ca(2+)-permeability and thereby in excitotoxic cell death of the surrounding neurons. Here we investigated how the GBM cells
Shoko Shimizu et al.
Glia, 62(5), 709-724 (2014-02-01)
Recent studies have shown changes in myelin genes and alterations in white matter structure in a wide range of psychiatric disorders. Here we report that DBZ, a central nervous system (CNS)-specific member of the DISC1 interactome, positively regulates the oligodendrocyte
Jureepon Roboon et al.
Frontiers in cellular neuroscience, 13, 258-258 (2019-06-28)
CD38 is an enzyme that catalyzes the synthesis of cyclic adenosine diphosphate-ribose from nicotinamide adenine dinucleotide (NAD+). We recently reported that this molecule regulates the maturation and differentiation of glial cells such as astrocytes and oligodendrocytes (OLs) in the developing
Ester Orav et al.
Molecular neurobiology, 56(11), 7473-7489 (2019-05-03)
Kainate type ionotropic glutamate receptors (KARs) are expressed in hippocampal interneurons and regulate interneuron excitability and GABAergic transmission. Neuropilin tolloid-like proteins (NETO1 and NETO2) act as KAR auxiliary subunits; however, their significance for various functions of KARs in GABAergic interneurons
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