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MAB1681

Sigma-Aldrich

Anti-Vimentin Antibody, clone LN-6

culture supernatant, clone LN-6, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

LN-6, monoclonal

reactividad de especies

human, mouse

fabricante / nombre comercial

Chemicon®

técnicas

immunohistochemistry: suitable (paraffin)

isotipo

IgM

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... VIM(7431)

Descripción general

Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.

Especificidad

Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.

Inmunógeno

Nuclei from adult human thymic biopsy specimens.

Aplicación

Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.

Descripción de destino

57-60 kDa

Forma física

Liquid tissue culture supernatant containing 0.02% sodium azide.

Nota de análisis

Control
Hyperplastic lymph nodes.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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The glomerulus is a highly complex system, composed of different interdependent cell types that are subjected to various mechanical stimuli. These stimuli regulate multiple cellular functions, and changes in these functions may contribute to tissue damage and disease progression. To

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