GHRT-89HK

Human Ghrelin (TOTAL) RIA

• Código UNSPSC: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Propiedades

• grado: for protein analysis
• Nivel de calidad: 100
• descripción: ED₈₀ = 395 ± 88 pg/mL ED₅₀ = 895 ± 177 pg/mL ED₂₀ = 2015 ± 382 pg/mL ; analytes available: Ghrelin
• Características: accuracy 90–96%
• reactividad de especies: human
• intervalo de medición de la sensibilidad: 100-10000 pg/mL
• técnicas: radioimmunoassay: suitable
• Nº de acceso UniProt: Q9UBU3
• método de detección: radioactive

Descripción

Descripción general

FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.

Aplicación

Two-day disequilibrium assay at 4°C. Sample volume: ≤ 100 μL Plasma (collected on ice) recommended

Nota de análisis

Linearity 99–146%

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H226,H302 + H332,H311,H319,H336,H411
• Consejos de prudencia: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 3 - STOT SE 3
• Órganos de actuación: Central nervous system
• Código de clase de almacenamiento: 3 - Flammable liquids