AP309P
Goat Anti-Human IgG Antibody, HRP conjugate
1.0 mg/mL, Chemicon®
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.46
Productos recomendados
origen biológico
goat
Nivel de calidad
conjugado
peroxidase conjugate
forma del anticuerpo
affinity purified immunoglobulin
tipo de anticuerpo
secondary antibodies
clon
polyclonal
formulario
lyophilized
reactividad de especies
human
fabricante / nombre comercial
Chemicon®
concentración
1.0 mg/mL
técnicas
ELISA: suitable
western blot: suitable
isotipo
IgG
Condiciones de envío
wet ice
temp. de almacenamiento
2-8°C
modificación del objetivo postraduccional
unmodified
Categorías relacionadas
Descripción general
Immunoglobulin G (IgG) is the main type of glycoprotein antibody found in human serum, secreted by the B cells. It is found in blood and comprises four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains. These chains are inter-linked by di-sulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3 and IgG4. IgG has the longest serum half-life compared to other immunoglobulins.
Especificidad
Specific for human IgG gamma chain. The cross-reactivities of anti-human IgG (gamma) antibody are tested in an ELISA. Minimal cross-reactivity to light chains.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
Aplicación
ELISA: 1:3,000
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
Acciones bioquímicas o fisiológicas
Immunoglobulin G (IgG) initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a vital role in antibody-dependent cell-mediated cytotoxicity (ADCC) and might be associated with allergy. Maternal IgG is transferred to the fetus through the placenta that is crucial for the immune defense of the neonate against infections. Digestion of IgG by papain results in the production of fragment antigen-binding (Fab). Pepsin digestion of IgG leads to the generation of fragment crystallizable (Fc). Levels of IgG in severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infected patients can be used as a potential tool to evaluate the severity and prognosis of coronavirus disease 2019 (COVID-19).
Forma física
ImmunoAffinity Purified
0.01M PBS, PH7.1, with 15mg/mL BSA
0.01M PBS, PH7.1, with 15mg/mL BSA
Almacenamiento y estabilidad
The undiluted antibody is stable at 2-8°C for 12 months. Do not store in a diluted format. DO NOT FREEZE.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
13 - Non Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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