ABF207

Anti-TIRP Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: TIR domain-containing adapter molecule 2, TICAM-2, Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: rat, human, mouse
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Nº de acceso UniProt: Q86XR7
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TICAM2(353376)

Descripción

Descripción general

Toll/interleukin-1 receptor domain-containing protein (TIRP), also known as TIR domain-containing adapter molecule 2 (TICAM2), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TIRP is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.

Especificidad

This antibody recognizes the C-terminus of TIRP.

Inmunógeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human TIRP.

Aplicación

Detect Toll/interleukin-1 receptor domain-containing protein using this rabbit polyclonal antibody, Anti-TIRP Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected TIRP in mouse kidney tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIRP in mouse kidney cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Calidad

Evaluated by Western Blotting in human, mouse, and rat kidney tissue lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected TIRP in human, mouse, and rat kidney tissue lysates.

Descripción de destino

~26 kDa observed. Uncharacterized bands may appear in some lysates.

Forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human, mouse, and rat kidney tissue lysates

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable