ABD115

Anti-MUSTN1

from rabbit, purified by affinity chromatography

• Sinónimos: Musculoskeletal embryonic nuclear protein 1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human, mouse
• reactividad de especies (predicha por homología): rat (based on 100% sequence homology)
• envase: antibody small pack of 25 μg
• técnicas: immunohistochemistry: suitable (paraffin); western blot: suitable
• isotipo: IgG
• Nº de acceso NCBI: NP_995325.3
• Nº de acceso UniProt: Q8IVN3
• Condiciones de envío: ambient
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MUSTN1(389125)

Descripción

Descripción general

Musculoskeletal embryonic nuclear protein 1 (UniProt: Q8IVN3; also known a MUSTN1) is encoded by the MUSTN1 gene (Gene ID: 389125) in human. MUSTN1 is a small protein of the MUSTANG family that is found predominantly in the musculoskeletal system. It plays a role in the development and regeneration of the musculoskeletal system. It localizes to the nucleus and specifically, spatially in mesenchymal cells of the developing limbs and in the fracture callus in periosteal osteoprogenitor cells, proliferating chondrocytes, and young active osteoblasts. MUSTN1 sequence is highly homologous in vertebrates and contains a nuclear localization sequence without any other significant motifs. MUSTN1 is highly expressed during embryogenesis and is essential for chondrocyte proliferation and differentiation. (Ref.: Gersch, RP and Hadjiargyrou, M (2009). Bone 45(2); 330-338).

Especificidad

This rabbit polyclonal antibody detects Musculoskeletal embryonic nuclear protein 1 (MUSTN1) in human and mouse. It targets an epitope within 12 amino acids from the C-terminal region.

Inmunógeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to 12 amino acids from the C-terminal region of human Musculoskeletal embryonic nuclear protein 1.

Aplicación

Anti-MUSTN1, Cat. No. ABD115, is a rabbit polyclonal antibody that detects human and murine Musculoskeletal embryonic nuclear protein 1 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting.

Research Category
Cell Structure

Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.
Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.

Western Blotting Analysis: 2 µg/mL from a representative lot detected MUSTN1 in human heart tissue lysate.

Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected MUSTN1 in human skeletal muscle, mouse embryo, and mouse embryonic lung tissues.

Calidad

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected MUSTN1 in C2C12 cell lysate.

Descripción de destino

~13 kDa observed; 8.91 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Forma física

Affinity Purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine, 0.15 M NaCl, pH7.4 with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to lot specific datasheet.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Clase de riesgo para el agua (WGK): WGK 1