ABC1486

Anti-RIPK1 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Receptor-interacting serine/threonine-protein kinase 1, RIPK1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse, rat
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso UniProt: Q13546
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Ripk1(19766)

Descripción

Descripción general

Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).

Inmunógeno

Epitope: Near N-terminus

RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.

Aplicación

Immunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected RIPK1 in mouse kidney tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1.

Calidad

Evaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected RIPK1 in rat kidney tissue lysate.

Descripción de destino

~75 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to lot specific datasheet.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable