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AB5684

Sigma-Aldrich

Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3.

Chemicon®, from rabbit

Sinónimos:

MATH4b

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human, rat, mouse

fabricante / nombre comercial

Chemicon®

técnicas

immunohistochemistry: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... NEUROG3(50674)

Descripción general

Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation). Neurogenin-3 promotes pancreatic development.

Especificidad

Recognizes Neurogenin 3 (MATH4b), a Helix-loop-helix class of transcription factor.

Inmunógeno

Epitope: a.a. 80-93 of mouse Neurogenin 3.
Synthetic peptide, amino acids 80-93 of mouse Neurogenin 3.

Aplicación

Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3. detects level of Neurogenin-3 & has been published & validated for use in IH.
Immunohistochemistry: 1:200-1:1,000.
Immunocytochemistry: Cat. # AB5684 detects Neurogenin-3 in PC12 cells at 1:500 dilution.
Not recommended for Western blot
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers

Descripción de destino

~ 23 kDa

Forma física

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

Almacenamiento y estabilidad

Stable for 1 year at -20ºC from date of receipt.

Nota de análisis

Control
Rat brain tissue.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Peribiliary glands (PBGs) are niches in the biliary tree and containing heterogeneous endodermal stem/progenitors cells that can differentiate, in vitro and in vivo, toward pancreatic islets. The aim of this study was to evaluate, in experimental and human diabetes, proliferation
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Journal of diabetes, 9(7), 707-716 (2016-10-30)
β-Cells at different stages have different functions and capacity for proliferation, regenerative and apoptosis. The aim of the present study was to investigate whether there are changes in β-cell phonotype in the development of diabetes to identify potential β-cell targets
Tzu-Lei Kuo et al.
iScience, 26(1), 105881-105881 (2023-01-20)
ARID1A is a tumor suppressor gene mutated in 7-10% of pancreatic cancer patients. However, its function in pancreas development and endocrine regulation is unclear. We generated mice that lack Arid1a expression in the pancreas. Our results showed that deletion of
Fang-Xu Jiang et al.
Stem cells (Dayton, Ohio), 35(5), 1341-1354 (2017-01-17)
Developmental stage-specific differentiation of stem or progenitor cells into safe and functional cells is of fundamental importance in regenerative medicine, including β-cell replacement. However, the differentiation of islet progenitor cells (IPCs) into insulin-secreting β cells remains elusive. Here, we report
Guido Carpino et al.
Journal of anatomy, 228(3), 474-486 (2015-11-28)
Pancreatic duct glands (PDGs) are tubule-alveolar glands associated with the pancreatic duct system and can be considered the anatomical counterpart of peribiliary glands (PBGs) found within the biliary tree. Recently, we demonstrated that endodermal precursor niches exist fetally and postnatally

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