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368050

Granzyme B Inhibitor I

≥95% (HPLC), solid, Granzyme B inhibitor, Calbiochem®

Sinónimos:

Granzyme B Inhibitor I, Z-AAD-CMK

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A ustedes/SKUDisponibilidadPrecio
1 mg
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
136,00 €

Acerca de este artículo

Fórmula empírica (notación de Hill):
C19H24ClN3O7
Peso molecular:
441.86
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated

136,00 €

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Nombre del producto

Granzyme B Inhibitor I, The Granzyme B Inhibitor I controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Quality Segment

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

off-white

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A weak inhibitor of the human and murine granzyme B. Also inhibits the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2, a rat lymphocyte granule protease homologous to granzyme B (ID50 = 300 nM).
A weak inhibitor of the human and murine serine protease granzyme B. Also inhibits the apoptosis related DNA fragmentation in lymphocytes by fragmentin 2, a rat lymphocyte granule protease homologous to granzyme B (ID50 = 300 nM).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Granzyme B
Product does not compete with ATP.
Reversible: no
Target IC50: 300 nM against the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Z-Ala-Ala-Asp-CH₂Cl
Gong, B., et al. 1999. Cell Growth Different. 10, 491.
Shi, L., et al. 1992. J. Exp. Med. 176, 1521.
Odake, S., et al. 1991. Biochemistry30, 2217.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Este artículo
368055368056218773
Granzyme B Inhibitor I The Granzyme B Inhibitor I controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

368050

Granzyme B Inhibitor I

Granzyme B Inhibitor II The Granzyme B Inhibitor II, also referenced under CAS 1258003-96-1, controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

368055

Granzyme B Inhibitor II

Granzyme B Inhibitor IV The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

368056

Granzyme B Inhibitor IV

Caspase-8 Inhibitor I, Cell-Permeable The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

218773

Caspase-8 Inhibitor I, Cell-Permeable

form

solid

form

lyophilized solid

form

solid

form

lyophilized solid

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, desiccated

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

OK to freeze

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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