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Merck
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36-003

Sigma-Aldrich

Anti-phospho-MYPT1 (Thr850) Antibody

Upstate®, from rabbit

Sinónimos:

Anti-GUBS, Anti-M130, Anti-MBS, Anti-MYPT1

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

chicken, rat, human, mouse

fabricante / nombre comercial

Upstate®

técnicas

western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

phosphorylation (pThr850)

Información sobre el gen

human ... PPP1R12A(4659)

Especificidad

Recombinant truncated chicken MYPT1 phosphorylated on Thr850.

Inmunógeno

Peptide corresponding to amino acid residues 845-855 of chicken MYPT1; this sequence is identical to amino acids 848-858 of human MYPT1, with the phosphorylated Thr at position 853.

Aplicación

Detect phospho-MYPT1 (Thr850) using this Anti-phospho-MYPT1 (Thr850) Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Kinases & Phosphatases

Calidad

Routinely evaluated by immunoblot on phophorylated MYPT1 substrate

Descripción de destino

80 kDa

Forma física

Format: Purified
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
Protein A purified

Almacenamiento y estabilidad

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
MYPT1 substrate phosphorylated by ROKa/ROCK-II

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Nandy C Lopez et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(11), R1053-R1063 (2016-02-26)
Exposure to high-altitude chronic hypoxia during pregnancy may cause pulmonary hypertension in neonates, as a result of vasoconstriction and vascular remodeling. We hypothesized that susceptibility to pulmonary hypertension, due to an augmented expression and activity of the RhoA/Rho-kinase (ROCK) pathway
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Utsunomiya H, Takaguri A, Bourne AM, Elliott KJ, Akazawa S, Okuno Y, Kono R, Eguchi S
American Journal of Hypertension null
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
Nichols, RJ; Dzamko, N; Hutti, JE; Cantley, LC; Deak, M; Moran, J; Bamborough, P; Reith et al.
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Soo-Kyoung Choi,Duck-Sun Ahn,Young-Ho Lee
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