345736

Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain

Useful as a differentiation marker of tumor cell growth.

• Sinónimos: Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain, Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
• Fórmula empírica (notación de Hill): C₈₄H₁₄₆N₄O₃₉ · 2NH₄
• Peso molecular: 1872.14
• Código UNSPSC: 12352211
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥98% (TLC)
• formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: DMSO: soluble; chloroform/methanol (2:1): soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Disialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.



Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.

Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
Protein kinase C

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Irritant (B)

Nota de preparación

For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.

Reconstitución

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

Otras notas

Longee, D.C., et al. 1991. Acta Neuropathologica82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato.232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem.50, 733.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable