324903

Epiregulin, Human, Recombinant

Epiregulin, Human, Recombinant, consists of amino acids 63-108 and expressed in E. coli with an N-terminal methionine.

• Código UNSPSC: 12352203

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥97% (SDS-PAGE)
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• impurezas: <1.0 EU/μg protein Endotoxin
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Recombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.

Acciones bioquímicas o fisiológicas

ED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

Advertencia

Toxicity: Standard Handling (A)

Forma física

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

Reconstitución

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Otras notas

Mishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol.283, F1151.
Shirakata, Y., et al. 2000. J. Biol. Chem.275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem.273, 10496.
Das, S.K., et al. 1997. Dev. Biol.190, 178.
Komurasaki, T., et al. 1997. Oncogene15, 2841.
Toyoda, H., et al. 1997. Biochem. J.326, 69.
Toyoda, H., et al. 1995. J. Biol. Chem.270, 7495.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3