208690

Calmodulin, Bovine Brain

Calmodulin is a ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from bovine brain.

• Sinónimos: Calmodulin, Bovine Brain, CaM, Ca ²⁺/Calmodulin, CaM, Ca²⁺/Calmodulin
• Número de CAS: 73298-54-1
• Número MDL: MFCD00131869
• Código UNSPSC: 12352202

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥95% (SDS-PAGE)
• Formulario: lyophilized
• actividad específica: ≥12,500 units/mg protein
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: aqueous buffer: soluble; water: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

A ubiquitous Ca²⁺-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca²⁺-calmodulin complex is involved in the maintenance of intracellular Ca²⁺ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.



Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.

A ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin purified from bovine brain.

Advertencia

Toxicity: Standard Handling (A)

Definición de unidad

One unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.

Forma física

Lyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.

Otras notas

Carl, A., et al. 1990. J. Physiol.429, 205.
Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res.10, 417.
Cheung, W.T. 1979. Science207, 19.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.
Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg.15, 47.
Watterson, A., et al. 1976. J. Biol. Chem.251, 4501.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3