14-818-M

Met (D1246N) Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N, for use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propiedades

• origen biológico: human
• Nivel de calidad: 300
• recombinante: expressed in Sf21 cells
• mol peso: M_w 50.1 kDa
• fabricante / nombre comercial: Upstate^®
• técnicas: activity assay: suitable (kinase)
• Nº de acceso UniProt: J02958; P08581

Descripción

Descripción general

Met D1246N is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.

N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N

Product Source: expressed by baculovirus in Sf21 insect cells

Acciones bioquímicas o fisiológicas

Protein Target: Met

Target Sub-Family: TK

Envase

Available in 250 μg --call for pricing and availability and reference catalog number 14-818M when ordering the 250 μg size.

Forma física

Ni²⁺/NTA-agarose

Almacenamiento y estabilidad

6 months at -70°C

Otras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable