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M-005

Supelco

Morphine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C17H19NO3
Número de CAS:
57-27-2
Peso molecular:
285.34
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

300

formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

forensics and toxicology

formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35

InChI

1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1

Clave InChI

BQJCRHHNABKAKU-KBQPJGBKSA-N

Información sobre el gen

human ... OPRM1(4988)

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Descripción general

This certified analytical reference standard is suitable for a variety of GC/MS or LC/MS applications from pain prescription monitoring, clinical toxicology, and urine drug testing to pharmaceutical research and forensic analysis.

Morphine is a natural phenolic alkaloid, commonly used as an analgesic and anti-inflammatory properties. Sold under trade names including MS Contin®, Kadian®, Oramorph®, and Roxanol, morphine is also a commonly abused recreational drug due to its widespread availability and a high potential for addiction.

Aplicación

The certified reference solution (CRM) in solution can also be used as follows:
  • Development of a hydrogel-modified carbon paste electrode (HCPE) for the electrochemical determination of morphine in very low volume solutions using differential pulse voltammetry
  • Combination of magnetic molecularly imprinted solid phase extraction (MMISPE) with high-performance liquid chromatography (HPLC) to analyze urine samples for quantifying morphine
  • Electrochemical detection and measurement of morphine and 3,4-methylenedioxymethamphetamine (MDMA) in human urine and serum samples using carbon nanohorns modified with Pt nanoparticles (CNHs@PtNPs) based sensor
  • Simultaneous determination of morphine and naltrexone in bulk and their combined solid dosage formulations using a stability-indicating high-performance liquid chromatographic method combined with a photodiode array detector
  • Colorimetric estimation of morphine and ibuprofen in human serum and urine samples as per the difference in the aggregation of citrate-capped gold nanoparticles (AuNPs) analyzed by infra-red (IR) spectroscopy and transmission electron microscopy (TEM)

Características y beneficios

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Kadian is a registered trademark of Actavis Elizabeth LLC
MS Contin is a registered trademark of Purdue Frederick Company
Oramorph is a registered trademark of AAIPharma, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Producto relacionado

Referencia del producto
Descripción
Precios

M-031

Morphine-3-β-D-glucuronide solution, 1 mg/mL in methanol with 0.05% NaOH, ampule of 1 mL, certified reference material, Cerilliant®

D-033

Dihydromorphine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

E-052

Ethylmorphine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

IMPM-005-01

Morphine N-oxide solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

IMPM-005-05

10-Hydroxymorphine solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-003

Morphine-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-006

Morphine-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-017

Morphine-D3-3-β-D-glucuronide solution, 100 μg/mL in methanol with 0.05% NaOH, ampule of 1 mL, certified reference material, Cerilliant®

M-018

Morphine-3-β-D-glucuronide solution, 100 μg/mL in methanol: water ( 50:50(v/v)), ampule of 1 mL, certified reference material, Cerilliant®

M-030

Morphine solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-046

Morphine-6-β-D-glucuronide solution, 1.0 mg/mL in methanol: water (2:8), ampule of 1 mL, certified reference material, Cerilliant®

M-085

Morphine-D6 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-086

Morphine-D6 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-096

Morphine-6-β-D-glucuronide solution, 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®

M-120

Morphine-6-β-D-glucuronide-D3 solution, 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®

N-006

Normorphine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-005S

Morphine solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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In response.
Alain Gorgeat
Anesthesia and analgesia, 116(6), 1391-1391 (2013-07-12)
Beatrice Setnik et al.
Journal of opioid management, 9(2), 139-150 (2013-05-28)
To evaluate whether intact or crushed doses of an extended-release formulation of morphine sulfate surrounding an inner core of sequestered naltrexone (MSN) induces signs and symptoms of withdrawal in opioid-dependent patients. Randomized, double-blind, two-way crossover study. Single center. Fourteen patients
Importance of reducing pain during routine procedures.
Michael C Petty
Journal of the American Veterinary Medical Association, 242(8), 1048-1048 (2013-05-15)
Thitima Chinachoti et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(5), 589-594 (2013-06-12)
Presently, in Siriraj Hospital, intrathecal morphine is routinely used in spinal anesthesia for postoperative pain control in more than 600 cases per month with doses lower than 0.3 mg. However, the incidence of side effects is high. This retrospective data
A Bilir
Clinical and experimental obstetrics & gynecology, 40(1), 118-121 (2013-06-04)
Pain management has a particular importance after Cesarean section. This study was undertaken in order to document the efficacy and side-effects of epidural morphine instead of patient-controlled analgesia technique used for the control of post-cesarean pain during postoperative 24-48 hours.
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Artículos

Benefits of Ascentis Express Phenyl-Hexyl over Biphenyl for the Separation of Pain Management Opiates

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

Protocolos

LC/MS (TOF) Analysis of Drugs and Their Glucuronide Metabolites in Urine on Titan™ C18 After Solid Phase Extraction (SPE) Using Supel™-Select SCX, β-Glucuronidase Enzyme Digestion

-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

UHPLC/MS for Drug Detection in Urine

Optimize β-glucuronidase hydrolysis for glucuronide metabolite analysis considering factors like time, temperature, pH, and enzyme concentration.

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