860498P

Sphinganine (d18:0)

Avanti Research^™ - A Croda Brand

• Sinónimos: D-erythro-sphinganine
• Fórmula empírica (notación de Hill): C₁₈H₃₉NO₂
• Número de CAS: 764-22-7
• Peso molecular: 301.51
• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• formulario: powder
• envase: pkg of 1 × 10 mg (860498P-10mg); pkg of 1 × 100 mg (860498P-100mg); pkg of 1 × 25 mg (860498P-25mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand
• tipo de lípido: sphingolipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI: 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
• Clave InChI: OTKJDMGTUTTYMP-ZWKOTPCHSA-N

Descripción

Descripción general

Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.

Aplicación

Sphinganine (d18:0) has been used:

• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
• as a medium supplement to test its effect on growth of yeast cells
• in the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition

Acciones bioquímicas o fisiológicas

Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.

Envase

5 mL Amber Glass Screw Cap Vial (860498P-100mg)

5 mL Amber Glass Screw Cap Vial (860498P-10mg)

5 mL Amber Glass Screw Cap Vial (860498P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable