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Merck

850446P

Avanti

14:0-18:0 PC

1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder

Sinónimos:

1-tetradecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine; MSPC; PC(14:0/18:0)

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About This Item

Fórmula empírica (notación de Hill):
C40H80NO8P
Número de CAS:
Peso molecular:
734.04
Código UNSPSC:
51191904
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

powder

envase

pkg of 1 × 200 mg (850446P-200mg)
pkg of 1 × 25 mg (850446P-25mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand 850446P

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

Clave InChI

TYAQXZHDAGZOEO-KXQOOQHDSA-N

Descripción general

Phosphatidylcholine (PC) is one of the most important constituent of colon′s mucosal layer. 14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetrical lipid with long alkyl side chain.

Aplicación

14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:
  • in lipid bilayers to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
  • as an asymmetrical lipid component in liposomes to study the impact of bilayer area and lipid geometry and as liposomal solubilizing agents
  • to prepare a low temperature-sensitive liposome for thrombolytic studies

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) forms a hydrophobic surface in the mucus by acting as a surfactant resulting in the inhibition of penetrance of bacteria.

Envase

5 mL Amber Glass Screw Cap Vial (850446P-200mg)
5 mL Amber Glass Screw Cap Vial (850446P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Liposomes are well recognised for their ability to improve the delivery of a range of drugs. More commonly they are applied for the delivery of water-soluble drugs, but given their structural attributes, they can also be employed as solubilising agents
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Although great efforts have been undertaken to develop a nanoparticle-based drug delivery system (DDS) for the treatment of solid tumors, the therapeutic outcomes are still limited. Immune cells, which possess an intrinsic ability to phagocytose nanoparticles and are recruited by
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In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs

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