H5518
Hematoporphyrin
≥45%
Sinónimos:
8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid
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About This Item
Fórmula empírica (notación de Hill):
C34H38N4O6
Número de CAS:
Peso molecular:
598.69
Beilstein:
78957
Número CE:
Número MDL:
Código UNSPSC:
12352300
ID de la sustancia en PubChem:
Productos recomendados
concentración
≥45%
temp. de almacenamiento
−20°C
cadena SMILES
CC(O)c1c(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5CCC(O)=O)c(CCC(O)=O)c4C)c(C)c3C(C)O
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Precaución
Readily dehydrates to monohydroxyethylmonovinyldeuteroporphyrin
Código de clase de almacenamiento
13 - Non Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Mohammed Ahmed et al.
Indian journal of biochemistry & biophysics, 51(3), 175-187 (2014-09-11)
Interaction of proteins with small molecules is important in understanding delivery and transport of different therapeutic agents, including drugs. In the present study, we investigated the interaction between hematoporphyrin (HP), the principal component of photosensitizing drug with bovine serum albumin
Ilaria Postiglione et al.
International journal of molecular sciences, 16(9), 20375-20391 (2015-09-08)
Photofrin/photodynamic therapy (PDT) at sub-lethal doses induced a transient stall in proteasome activity in surviving A549 (p53(+/+)) and H1299 (p53(-/-)) cells as indicated by the time-dependent decline/recovery of chymotrypsin-like activity. Indeed, within 3 h of incubation, Photofrin invaded the cytoplasm
Chu-I Lee et al.
Journal of cellular biochemistry, 116(9), 2074-2085 (2015-04-29)
Neuroblastoma is one of the most aggressive cancers and has a complex form of differentiation. We hypothesized that advanced cellular differentiation may alter the susceptibility of neuroblastoma to photodynamic treatment (PDT) and confer selective survival advantage. We demonstrated that hematoporphyrin
Albish K Paul et al.
Photochemistry and photobiology, 91(6), 1348-1355 (2015-10-24)
Synthesis, photophysical and metal ion recognition properties of a series of amino acid-linked free-base and Zn-porphyrin derivatives (5-9) are reported. These porphyrin derivatives showed favorable photophysical properties including high molar extinction coefficients (>1 × 10(5) m(-1) cm(-1) for the Soret
Jisun Kim et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 43(9), 675-684 (2014-06-17)
Photodynamic therapy (PDT) is an anticancer treatment that generates excessive reactive oxygen species after photosensitizer treatments following specific wavelength irradiation. In another reports, PDT was regulated with autophagic cell death and apoptotic cell death. However, the mechanism of PDT resistance
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