D99234

Diethyl phosphite

98%

• Sinónimos: Diethoxyphosphine oxide, Diethyl acid phosphite, Diethyl hydrogen phosphite, Diethyl phosphonate, Hydrogen diethyl phosphite
• Fórmula lineal: (C₂H₅O)₂P(O)H
• Número de CAS: 762-04-9
• Peso molecular: 138.10
• Beilstein: 605759
• Número CE: 212-091-6
• Número MDL: MFCD00044573
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24894335
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• Análisis: 98%
• formulario: liquid
• índice de refracción: n20/D 1.407 (lit.)
• bp: 50-51 °C/2 mmHg (lit.)
• densidad: 1.072 g/mL at 25 °C (lit.)
• cadena SMILES: [H]P(=O)(OCC)OCC
• InChI: 1S/C4H11O3P/c1-3-6-8(5)7-4-2/h8H,3-4H2,1-2H3
• Clave InChI: MJUJXFBTEFXVKU-UHFFFAOYSA-N

Descripción

Descripción general

Diethyl phosphite is the organophosphorus compound used as a phosphorylating agent in organic synthesis.

Aplicación

Applications of diethyl phosphite (DEP):

• It can undergo condensation with aldehydes or ketones and an amine to form α-aminophosphonates under solvent-free and catalyst-free conditions.
• Reduction of gem-dibromo derivatives using diethyl phosphite in the presence of triethylamine gives monobromocyclopropanes.
• Along with 4-dimethylaminopyridine, it can be used as a ligand for nickel-catalyzed cross-coupling of aryl and heteroaryl bromides, chlorides or sulfonates with arylzinc reagents.
• It can be used for the catalytic asymmetric hydrophosphonylation of enones in the presence of a dinuclear zinc complex to form γ-oxo-phosphonates.
• DEP can undergo Michael addition to α,β-unsaturated malonates to form β-phosphonomalonates in the presence of recyclable nano γ-ferric oxide-pyridine based catalyst.

Información de seguridad

• Pictogramas: GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H317,H318
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P305 + P351 + P338 - P333 + P313
• Clasificaciones de peligro: Eye Dam. 1 - Skin Sens. 1B
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 179.6 °F - closed cup
• Punto de inflamabilidad (°C): 82 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves, type ABEK (EN14387) respirator filter