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Merck
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Documentos

764604

Sigma-Aldrich

Polyethylenimine, linear

average Mn 2100, PDI <1.3

Sinónimos:

PEI

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About This Item

Fórmula lineal:
(CH2CH2NH)n
Número de CAS:
9002-98-6
Código UNSPSC:
12162002
NACRES:
NA.23

formulario

liquid

mol peso

average Mn 2100

mp

59-64 °C

temperatura de transición

Tm 59-64 °C

PDI

<1.3

temp. de almacenamiento

2-8°C

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

Clave InChI

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Descripción general

Polyethylenimine(PEI) is a synthetic cationic polymerwith high charge density and chain flexibility. It is the most widelyinvestigated cationic polymer for non-viral delivery of nucleic acids. LinearPEI can be an effective carrier for a wide range of gene medicine including DNAplasmids, small interfering RNAs, and mRNAs. It protects the DNA from theacidic environment and ensures the release of DNA to the cytoplasm.

Aplicación

  • Water-soluble linear poly (ethylenimine) as a superior bifunctional binder for lithium–sulfur batteries: Demonstrates the utility of water-soluble linear polyethylenimine as an effective bifunctional binder that enhances the cycle stability and efficiency of lithium-sulfur batteries, pivotal for advancing battery technology (Liao et al., 2018).

Palabra de señalización

Danger

Frases de peligro

H302,H317,H318,H411

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Lei Feng et al.
Engineering in life sciences, 20(8), 320-330 (2020-08-11)
As the main immunogen that could stimulate neutralized antibody in pigs, recombinant E2 protein of CSFV was expressed in CHO-dhfr-cells driven by endogenous Txnip promoter from Chinese hamster. Different fragments of Txnip promoter were amplified by PCR from isolated genomic
Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with

Artículos

Delivery of Nucleic Acids Using Polymers

Delivery of Nucleic Acids Using Polymers

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Progress on Nonviral Delivery for CRISPR/Cas9

CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.

Ver todo

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